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S100 calcium-binding protein G
Symbols S100G ; CABP; CABP1; CABP9K; CALB3
External IDs OMIM302020 MGI104528 HomoloGene36150 GeneCards: S100G Gene
RNA expression pattern
PBB GE S100G 207885 at tn.png
More reference expression data
Species Human Mouse
Entrez 795 12309
Ensembl ENSG00000169906 ENSMUSG00000040808
UniProt P29377 P97816
RefSeq (mRNA) NM_004057 NM_009789
RefSeq (protein) NP_004048 NP_033919
Location (UCSC) Chr X:
16.67 – 16.67 Mb
Chr X:
162.96 – 162.96 Mb
PubMed search [1] [2]
See also: Calbindin

S100 calcium-binding protein G (S100G) is a protein that in humans is encoded by the S100G gene.[1][2][3]

This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles.[3]


  1. ^ Howard A, Legon S, Spurr NK, Walters JR (1992). "Molecular cloning and chromosomal assignment of human calbindin-D9k". Biochem Biophys Res Commun 185 (2): 663–9. doi:10.1016/0006-291X(92)91676-H. PMID 1610358. 
  2. ^ Jeung EB, Krisinger J, Dann JL, Leung PC (Sep 1992). "Molecular cloning of the full-length cDNA encoding the human calbindin-D9k". FEBS Lett 307 (2): 224–8. doi:10.1016/0014-5793(92)80772-9. PMID 1379540. 
  3. ^ a b "Entrez Gene: S100G S100 calcium binding protein G". 

Further reading[edit]