SEC14L1

SEC14L1
Identifiers
Aliases	SEC14L1, PRELID4A, SEC14L, SEC14 like lipid binding 1
External IDs	OMIM: 601504 MGI: 1921386 HomoloGene: 37719 GeneCards: SEC14L1
Gene location (Human) Chr. Chromosome 17 (human) Band 17q25.2-q25.3 Start 77,088,749 bp End 77,217,101 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 E2 Start 117,005,994 bp End 117,050,094 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in internal globus pallidus blood inferior olivary nucleus lower lobe of lung right lung pericardium olfactory bulb sperm Region I of hippocampus proper superficial temporal artery Top expressed in submandibular gland superior frontal gyrus lens molar entorhinal cortex spermatid cerebellar cortex lacrimal gland parotid gland hippocampus proper More reference expression data BioGPS n/a
Gene ontology Molecular function RIG-I binding protein binding molecular function regulator Cellular component cytoplasm Golgi apparatus nucleoplasm cytosol Biological process negative regulation of signal transduction innate immune response negative regulation of RIG-I signaling pathway choline transport immune system process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6397 74136 Ensembl ENSG00000129657 ENSMUSG00000020823 UniProt Q92503 A8Y5H7 RefSeq (mRNA) NM_003003 NM_001039573 NM_001143998 NM_001143999 NM_001144001 NM_001204408 NM_001204410 NM_001166506 NM_001166507 NM_028777 NM_001363165 RefSeq (protein) NP_001034662 NP_001137470 NP_001137471 NP_001137473 NP_001191337 NP_001191339 NP_002994 NP_001159978 NP_001159979 NP_083053 NP_001350094 Location (UCSC) Chr 17: 77.09 – 77.22 Mb Chr 11: 117.01 – 117.05 Mb PubMed search
Wikidata
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SEC14-like protein 1 is a protein that in humans is encoded by the SEC14L1 gene.

The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Kalikin LM, Bugeaud EM, Palmbos PL, et al. (2002). "Genomic characterization of human SEC14L1 splice variants within a 17q25 candidate tumor suppressor gene region and identification of an unrelated embedded expressed sequence tag" (PDF). Mamm. Genome. 12 (12): 925–9. doi:10.1007/s00335-001-2073-3. hdl:2027.42/42124. PMID 11707779. S2CID 1547107.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.