SEC14L2

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SEC14-like 2 (S. cerevisiae)
Protein SEC14L2 PDB 1o6u.png
PDB rendering based on 1o6u.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SEC14L2 ; C22orf6; SPF; TAP; TAP1
External IDs OMIM607558 MGI1915065 HomoloGene8245 GeneCards: SEC14L2 Gene
RNA expression pattern
PBB GE SEC14L2 204541 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 23541 67815
Ensembl ENSG00000100003 ENSMUSG00000003585
UniProt O76054 Q99J08
RefSeq (mRNA) NM_001204204 NM_144520
RefSeq (protein) NP_001191133 NP_653103
Location (UCSC) Chr 22:
30.79 – 30.82 Mb
Chr 11:
4.1 – 4.12 Mb
PubMed search [1] [2]

SEC14-like protein 2 is a protein that in humans is encoded by the SEC14L2 gene.[1][2]

This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway.[2]

References[edit]

  1. ^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M (Dec 1999). "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208. 
  2. ^ a b "Entrez Gene: SEC14L2 SEC14-like 2 (S. cerevisiae)". 

Further reading[edit]