SEGPHOS
From Wikipedia, the free encyclopedia
| SEGPHOS | |
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4,4'-Bi-1,3-benzodioxole-5,5'-diylbis(diphenylphosphane) |
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Other names
SEGPHOS |
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| Identifiers | |
| CAS number | 244261-66-3, (R) [210169-54-3] (S) |
| Properties | |
| Molecular formula | C38H28O4P2 |
| Molar mass | 610.57 g/mol |
| Appearance | colorless solid |
| Solubility in water | organic solvents |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
SEGPHOS is a chiral ligand that is used in asymmetric synthesis.[1] It was developed after BINAP and was investigated since it has a narrower dihedral angle between the aromatic faces. This was predicted and then confirmed to increase the enantioselectivity and activity of metal complexes of SEGPHOS.
References [edit]
- ^ Shimizu, H., Nagasaki, I., Matsumura, K., Sayo, N., Saito, T. (2007). "Developments in Asymmetric Hydrogenation from an Industrial Perspective". Acc. Chem. Res. 40 (12): 1385–1393. doi:10.1021/ar700101x. PMID 17685581.
