SEMA6A

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Sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Identifiers
Symbols SEMA6A ; HT018; SEMA; SEMA6A1; SEMAQ; VIA
External IDs OMIM605885 MGI1203727 HomoloGene32426 GeneCards: SEMA6A Gene
RNA expression pattern
PBB GE SEMA6A 220454 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 57556 20358
Ensembl ENSG00000092421 ENSMUSG00000019647
UniProt Q9H2E6 O35464
RefSeq (mRNA) NM_001300780 NM_018744
RefSeq (protein) NP_001287709 NP_061214
Location (UCSC) Chr 5:
115.78 – 115.91 Mb
Chr 18:
47.24 – 47.37 Mb
PubMed search [1] [2]

Semaphorin-6A is a protein that in humans is encoded by the SEMA6A gene.[1][2][3]

In melanocytic cells SEMA6A gene expression may be regulated by MITF.[4]


References[edit]

  1. ^ Zhou L, White FA, Lentz SI, Wright DE, Fisher DA, Snider WD (Sep 1997). "Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I". Mol Cell Neurosci 9 (1): 26–41. doi:10.1006/mcne.1997.0607. PMID 9204478. 
  2. ^ Klostermann A, Lutz B, Gertler F, Behl C (Jan 2001). "The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain". J Biol Chem 275 (50): 39647–53. doi:10.1074/jbc.M006316200. PMID 10993894. 
  3. ^ "Entrez Gene: SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A". 
  4. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 

Further reading[edit]