SERPINB9

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Serpin peptidase inhibitor, clade B (ovalbumin), member 9
Identifiers
Symbols SERPINB9 ; CAP-3; CAP3; PI-9; PI9
External IDs OMIM601799 MGI106603 HomoloGene37888 GeneCards: SERPINB9 Gene
RNA expression pattern
PBB GE SERPINB9 209723 at tn.png
PBB GE SERPINB9 209722 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5272 20723
Ensembl ENSG00000170542 ENSMUSG00000045827
UniProt P50453 O08797
RefSeq (mRNA) NM_004155 NM_009256
RefSeq (protein) NP_004146 NP_033282
Location (UCSC) Chr 6:
2.89 – 2.9 Mb
Chr 13:
33 – 33.02 Mb
PubMed search [1] [2]

Serpin B9 is a protein that in humans is encoded by the SERPINB9 gene.[1][2][3]

PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis (Sprecher et al., 1995).[supplied by OMIM][3]

See also[edit]

References[edit]

  1. ^ Sprecher CA, Morgenstern KA, Mathewes S, Dahlen JR, Schrader SK, Foster DC, Kisiel W (Jan 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem 270 (50): 29854–61. doi:10.1074/jbc.270.50.29854. PMID 8530382. 
  2. ^ Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI (Feb 1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet 82 (3–4): 273–7. doi:10.1159/000015118. PMID 9858835. 
  3. ^ a b "Entrez Gene: SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.