SERTAD1

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SERTA domain containing 1
Identifiers
Symbols SERTAD1 ; SEI1; TRIP-Br1
External IDs MGI1913438 HomoloGene8365 GeneCards: SERTAD1 Gene
RNA expression pattern
PBB GE SERTAD1 gnf1h00138 at tn.png
PBB GE SERTAD1 gnf1h00139 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 29950 55942
Ensembl ENSG00000197019 ENSMUSG00000008384
UniProt Q9UHV2 Q9JL10
RefSeq (mRNA) NM_013376 NM_018820
RefSeq (protein) NP_037508 NP_061290
Location (UCSC) Chr 19:
40.93 – 40.93 Mb
Chr 7:
27.49 – 27.49 Mb
PubMed search [1] [2]

SERTA domain-containing protein 1 is a protein that in humans is encoded by the SERTAD1 gene.[1][2][3]


Interactions[edit]

SERTAD1 has been shown to interact with P16,[2][4] Cyclin-dependent kinase 4[2][4] and CREB-binding protein.[5]

References[edit]

  1. ^ Besley GT, Broadhead DM, Lawlor E (Nov 1984). "Acid esterase deficiency: comparison of biochemical findings in infantile and adult forms". J Inherit Metab Dis. 7 Suppl 2: 155–6. doi:10.1007/978-94-009-5612-4_52. PMID 6434876. 
  2. ^ a b c Sugimoto M, Nakamura T, Ohtani N, Hampson L, Hampson IN, Shimamoto A, Furuichi Y, Okumura K, Niwa S, Taya Y, Hara E (Jan 2000). "Regulation of CDK4 activity by a novel CDK4-binding protein, p34SEI-1". Genes Dev 13 (22): 3027–33. doi:10.1101/gad.13.22.3027. PMC 317153. PMID 10580009. 
  3. ^ "Entrez Gene: SERTAD1 SERTA domain containing 1". 
  4. ^ a b Li, Junan; Melvin W Scott; Tsai Ming-Daw; Muscarella Peter (Apr 2004). "The nuclear protein p34SEI-1 regulates the kinase activity of cyclin-dependent kinase 4 in a concentration-dependent manner". Biochemistry (United States) 43 (14): 4394–9. doi:10.1021/bi035601s. ISSN 0006-2960. PMID 15065884. 
  5. ^ Hirose, Takuji; Fujii Ryouji; Nakamura Hiroshi; Aratani Satoko; Fujita Hidetoshi; Nakazawa Minako; Nakamura Kohzo; Nishioka Kusuki; Nakajima Toshihiro (Jun 2003). "Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP". Int. J. Mol. Med. (Greece) 11 (6): 705–12. doi:10.3892/ijmm.11.6.705. ISSN 1107-3756. PMID 12736710. 

Further reading[edit]