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Splicing regulatory glutamine/lysine-rich protein 1
Symbols SREK1 ; SFRS12; SRrp508; SRrp86
External IDs OMIM609268 MGI2145245 HomoloGene10581 GeneCards: SREK1 Gene
RNA expression pattern
PBB GE SFRS12 212721 at tn.png
More reference expression data
Species Human Mouse
Entrez 140890 218543
Ensembl ENSG00000153914 ENSMUSG00000032621
UniProt Q8WXA9 Q8BZX4
RefSeq (mRNA) NM_001077199 NM_172592
RefSeq (protein) NP_001070667 NP_766180
Location (UCSC) Chr 5:
65.44 – 65.48 Mb
Chr 13:
103.74 – 103.76 Mb
PubMed search [1] [2]

Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.[1][2]

SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM][2]


  1. ^ Zhang DL, Sun XJ, Ling LJ, Chen RS, Ma DL (Jun 2002). "[Molecular cloning, characterization, chromosomal assignment, genomic organization and verification of SFRS12(SRrp508), a novel member of human SR protein superfamily and a human homolog of rat SRrp86]". Yi Chuan Xue Bao 29 (5): 377–83. PMID 12043562. 
  2. ^ a b "Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12". 

Further reading[edit]