Small glutamine-rich tetratricopeptide repeat-containing protein alpha is a protein that in humans is encoded by the SGTAgene.SGTAorthologs have also been identified in several mammals for which complete genome data are available.
This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function.
^Kordes E, Savelyeva L, Schwab M, Rommelaere J, Jauniaux JC, Cziepluch C (May 1999). "Isolation and characterization of human SGT and identification of homologues in Saccharomyces cerevisiae and Caenorhabditis elegans". Genomics52 (1): 90–4. doi:10.1006/geno.1998.5385. PMID9740675.
Heavner GA, Audhya T, Goldstein G (1990). "Peptide analogs of thymopentin distinguish distinct thymopoietin receptor specificities on two human T cell lines". Regul. Pept.27 (2): 257–62. doi:10.1016/0167-0115(90)90044-W. PMID2158125.
Callahan MA, Handley MA, Lee YH et al. (1998). "Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family". J. Virol.72 (10): 8461. PMID9766974.
Liu FH, Wu SJ, Hu SM et al. (1999). "Specific interaction of the 70-kDa heat shock cognate protein with the tetratricopeptide repeats". J. Biol. Chem.274 (48): 34425–32. doi:10.1074/jbc.274.48.34425. PMID10567422.
Handley MA, Paddock S, Dall A, Panganiban AT (2002). "Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag protein". Virology291 (2): 198–207. doi:10.1006/viro.2001.1166. PMID11878889.
Pai MT, Yang CS, Tzeng SR et al. (2004). "1H, 15N and 13C resonance assignments of the tetratricopeptide repeat (TPR) domain of hSGT". J. Biomol. NMR26 (4): 381–2. doi:10.1023/A:1024029117511. PMID12815268.
Lehner B, Semple JI, Brown SE et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID14667819.
Winnefeld M, Rommelaere J, Cziepluch C (2004). "The human small glutamine-rich TPR-containing protein is required for progress through cell division". Exp. Cell Res.293 (1): 43–57. doi:10.1016/j.yexcr.2003.09.028. PMID14729056.