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SH2 domain containing 2A
Symbols SH2D2A ; F2771; SCAP; TSAD; VRAP
External IDs OMIM604514 MGI1351596 HomoloGene2958 GeneCards: SH2D2A Gene
RNA expression pattern
PBB GE SH2D2A 207351 s at tn.png
More reference expression data
Species Human Mouse
Entrez 9047 27371
Ensembl ENSG00000027869 ENSMUSG00000028071
UniProt Q9NP31 Q9QXK9
RefSeq (mRNA) NM_001161441 NM_001025571
RefSeq (protein) NP_001154913 NP_001020742
Location (UCSC) Chr 1:
156.78 – 156.79 Mb
Chr 3:
87.85 – 87.86 Mb
PubMed search [1] [2]

SH2 domain-containing protein 2A is a protein that in humans is encoded by the SH2D2A gene.[1][2]


SH2D2A has been shown to interact with MAP3K2.[3]


  1. ^ Spurkland A, Brinchmann JE, Markussen G, Pedeutour F, Munthe E, Lea T, Vartdal F, Aasheim HC (March 1998). "Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites". J Biol Chem 273 (8): 4539–46. doi:10.1074/jbc.273.8.4539. PMID 9468509. 
  2. ^ "Entrez Gene: SH2D2A SH2 domain protein 2A". 
  3. ^ Sun, W; Kesavan K; Schaefer B C; Garrington T P; Ware M; Johnson N L; Gelfand E W; Johnson G L (February 2001). "MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway". J. Biol. Chem. (United States) 276 (7): 5093–100. doi:10.1074/jbc.M003719200. ISSN 0021-9258. PMID 11073940. 

Further reading[edit]