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The initialism SIMPLE may refer to:
- SIMPLE (dark matter experiment)
- SIMPLE (instant messaging protocol)
- SIMPLE (military communications protocol)
- SiMPLE, a computer programming language created in 1995
- SIMPLE algorithm, in computational fluid dynamics
- SIMPLE IRA, a type of employer-provided retirement plan in the United States
|This disambiguation page lists articles associated with the title SIMPLE.
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