Monocarboxylate transporter 10

From Wikipedia, the free encyclopedia
  (Redirected from SLC16A10)
Jump to: navigation, search
Solute carrier family 16, member 10 (aromatic amino acid transporter)
Symbols SLC16A10 ; MCT10; PRO0813; TAT1
External IDs OMIM607550 HomoloGene75089 IUPHAR: 993 GeneCards: SLC16A10 Gene
Species Human Mouse
Entrez 117247 72472
Ensembl ENSG00000112394 ENSMUSG00000019838
UniProt Q8TF71 Q3U9N9
RefSeq (mRNA) NM_018593 NM_001114332
RefSeq (protein) NP_061063 NP_001107804
Location (UCSC) Chr 6:
111.41 – 111.55 Mb
Chr 10:
40.03 – 40.14 Mb
PubMed search [1] [2]

Monocarboxylate transporter 10 (MCT 10), also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene.[1][2][3] SLC16A10 is a member of the solute carrier family.


SLC16A10 mediates Na+-independent transport of tryptophan, tyrosine, phenylalanine, and L-DOPA.[3]

See also[edit]


  1. ^ "Entrez Gene: solute carrier family 16". 
  2. ^ Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H (May 2001). "Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters". J. Biol. Chem. 276 (20): 17221–8. doi:10.1074/jbc.M009462200. PMID 11278508. 
  3. ^ a b Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H (January 2002). "The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location". Genomics 79 (1): 95–103. doi:10.1006/geno.2001.6678. PMID 11827462. 

Further reading[edit]