SLC22A7

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Solute carrier family 22 (organic anion transporter), member 7
Identifiers
Symbols SLC22A7 ; NLT; OAT2
External IDs OMIM604995 MGI1859559 HomoloGene21328 GeneCards: SLC22A7 Gene
RNA expression pattern
PBB GE SLC22A7 220554 at tn.png
PBB GE SLC22A7 221661 at tn.png
PBB GE SLC22A7 221662 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10864 108114
Ensembl ENSG00000137204 ENSMUSG00000067144
UniProt Q9Y694 Q91WU2
RefSeq (mRNA) NM_006672 NM_144856
RefSeq (protein) NP_006663 NP_659105
Location (UCSC) Chr 6:
43.26 – 43.27 Mb
Chr 17:
46.43 – 46.44 Mb
PubMed search [1] [2]

Solute carrier family 22 member 7 is a protein that in humans is encoded by the SLC22A7 gene.[1][2][3]

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.[3]

Interactive pathway map[edit]

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article
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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article
|{{{bSize}}}px|alt=Fluorouracil (5-FU) Activity edit|]]
Fluorouracil (5-FU) Activity edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601". 

See also[edit]

References[edit]

  1. ^ Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H (Jul 1998). "Identification of multispecific organic anion transporter 2 expressed predominantly in the liver". FEBS Lett 429 (2): 179–82. doi:10.1016/S0014-5793(98)00585-7. PMID 9650585. 
  2. ^ Kok LD, Siu SS, Fung KP, Tsui SK, Lee CY, Waye MM (Jun 2000). "Assignment of liver-specific organic anion transporter (SLC22A7) to human chromosome 6 bands p21.2→p21.1 using radiation hybrids". Cytogenet Cell Genet 88 (1–2): 76–7. doi:10.1159/000015489. PMID 10773670. 
  3. ^ a b "Entrez Gene: SLC22A7 solute carrier family 22 (organic anion transporter), member 7". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.