SLC23A1

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Solute carrier family 23 (nucleobase transporters), member 1
Identifiers
Symbols SLC23A1 ; SLC23A2; SVCT1; YSPL3
External IDs OMIM603790 MGI1341903 HomoloGene40769 GeneCards: SLC23A1 Gene
Orthologs
Species Human Mouse
Entrez 9963 20522
Ensembl ENSG00000170482 ENSMUSG00000024354
UniProt Q9UHI7 Q9Z2J0
RefSeq (mRNA) NM_005847 NM_011397
RefSeq (protein) NP_005838 NP_035527
Location (UCSC) Chr 5:
138.7 – 138.72 Mb
Chr 18:
35.61 – 35.63 Mb
PubMed search [1] [2]

Solute carrier family 23 member 1 is a protein that in humans is encoded by the SLC23A1 gene.[1][2][3]

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2.[3]

See also[edit]

References[edit]

  1. ^ Faaland CA, Race JE, Ricken G, Warner FJ, Williams WJ, Holtzman EJ (Dec 1998). "Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters". Biochim Biophys Acta 1442 (2–3): 353–60. doi:10.1016/S0167-4781(98)00151-1. PMID 9804989. 
  2. ^ Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA (Jun 1999). "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature 399 (6731): 70–5. doi:10.1038/19986. PMID 10331392. 
  3. ^ a b "Entrez Gene: SLC23A1 solute carrier family 23 (nucleobase transporters), member 1". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.