SLC23A2

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Solute carrier family 23 (nucleobase transporters), member 2
Identifiers
Symbols SLC23A2 ; NBTL1; SLC23A1; SVCT2; YSPL2
External IDs OMIM603791 MGI1859682 HomoloGene68440 ChEMBL: 3271 GeneCards: SLC23A2 Gene
RNA expression pattern
PBB GE SLC23A2 209236 at tn.png
PBB GE SLC23A2 209237 s at tn.png
PBB GE SLC23A2 211572 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9962 54338
Ensembl ENSG00000089057 ENSMUSG00000027340
UniProt Q9UGH3 Q9EPR4
RefSeq (mRNA) NM_005116 NM_018824
RefSeq (protein) NP_005107 NP_061294
Location (UCSC) Chr 20:
4.83 – 4.99 Mb
Chr 2:
132.05 – 132.15 Mb
PubMed search [1] [2]

Solute carrier family 23 member 2 is a protein that in humans is encoded by the SLC23A2 gene.[1][2][3]

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.[3]

See also[edit]

References[edit]

  1. ^ Faaland CA, Race JE, Ricken G, Warner FJ, Williams WJ, Holtzman EJ (Dec 1998). "Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters". Biochim Biophys Acta 1442 (2-3): 353–60. doi:10.1016/S0167-4781(98)00151-1. PMID 9804989. 
  2. ^ Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA (Jun 1999). "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature 399 (6731): 70–5. doi:10.1038/19986. PMID 10331392. 
  3. ^ a b "Entrez Gene: SLC23A2 solute carrier family 23 (nucleobase transporters), member 2". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.