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Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
Protein SLC25A4 PDB 1okc.png
PDB rendering based on 1okc.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols SLC25A4 ; 1; AAC1; ANT; ANT 1; ANT1; MTDPS12; PEO2; PEO3; T1
External IDs OMIM103220 MGI1353495 HomoloGene36058 ChEMBL: 1879 GeneCards: SLC25A4 Gene
RNA expression pattern
PBB GE SLC25A4 202825 at tn.png
More reference expression data
Species Human Mouse
Entrez 291 11739
Ensembl ENSG00000151729 ENSMUSG00000031633
UniProt P12235 P48962
RefSeq (mRNA) NM_001151 NM_007450
RefSeq (protein) NP_001142 NP_031476
Location (UCSC) Chr 4:
186.06 – 186.07 Mb
Chr 8:
46.21 – 46.21 Mb
PubMed search [1] [2]

ADP/ATP translocase 1 is an enzyme that in humans is encoded by the SLC25A4 gene or adenine nucleotide translocator, ANT.[1][2]


SLC25A4 has been shown to interact with Bcl-2-associated X protein.[3]


  1. ^ Fan YS, Yang HM, Lin CC (Jun 1992). "Assignment of the human muscle adenine nucleotide translocator gene (ANT1) to 4q35 by fluorescence in situ hybridization". Cytogenet Cell Genet 60 (1): 29–30. doi:10.1159/000133288. PMID 1582253. 
  2. ^ "Entrez Gene: SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4". 
  3. ^ Marzo, I; Brenner C, Zamzami N, Jürgensmeier J M, Susin S A, Vieira H L, Prévost M C, Xie Z, Matsuyama S, Reed J C, Kroemer G (Sep 1998). "Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis". Science (UNITED STATES) 281 (5385): 2027–31. doi:10.1126/science.281.5385.2027. ISSN 0036-8075. PMID 9748162. 

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