SLC26A7

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Solute carrier family 26 (anion exchanger), member 7
Identifiers
Symbols SLC26A7 ; SUT2
External IDs OMIM608479 MGI2384791 HomoloGene13770 GeneCards: SLC26A7 Gene
Orthologs
Species Human Mouse
Entrez 115111 208890
Ensembl ENSG00000147606 ENSMUSG00000040569
UniProt Q8TE54 Q8R2Z3
RefSeq (mRNA) NM_001282356 NM_145947
RefSeq (protein) NP_001269285 NP_666059
Location (UCSC) Chr 8:
92.22 – 92.41 Mb
Chr 4:
14.5 – 14.62 Mb
PubMed search [1] [2]

Anion exchange transporter is a protein that in humans is encoded by the SLC26A7 gene.[1][2][3][4]

This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Splice variants that use both alternate transcription initiation and polyadenylation sites have been described for this gene.[4]

See also[edit]

References[edit]

  1. ^ Lohi H, Kujala M, Makela S, Lehtonen E, Kestila M, Saarialho-Kere U, Markovich D, Kere J (Apr 2002). "Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9". J Biol Chem 277 (16): 14246–54. doi:10.1074/jbc.M111802200. PMID 11834742. 
  2. ^ Vincourt JB, Jullien D, Kossida S, Amalric F, Girard JP (Feb 2002). "Molecular cloning of SLC26A7, a novel member of the SLC26 sulfate/anion transporter family, from high endothelial venules and kidney". Genomics 79 (2): 249–56. doi:10.1006/geno.2002.6689. PMID 11829495. 
  3. ^ Xu J, Worrell RT, Li HC, Barone SL, Petrovic S, Amlal H, Soleimani M (Mar 2006). "Chloride/bicarbonate exchanger SLC26A7 is localized in endosomes in medullary collecting duct cells and is targeted to the basolateral membrane in hypertonicity and potassium depletion". J Am Soc Nephrol 17 (4): 956–67. doi:10.1681/ASN.2005111174. PMID 16524946. 
  4. ^ a b "Entrez Gene: SLC26A7 solute carrier family 26, member 7". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.