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Solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Symbols SLC5A3 ; SMIT; SMIT1; SMIT2
External IDs OMIM600444 MGI1858226 HomoloGene31412 IUPHAR: 924 GeneCards: SLC5A3 Gene
Species Human Mouse
Entrez 6526 53881
Ensembl ENSG00000198743 ENSMUSG00000089774
UniProt P53794 Q9JKZ2
RefSeq (mRNA) NM_006933 NM_017391
RefSeq (protein) NP_008864 NP_059087
Location (UCSC) Chr 21:
35.45 – 35.48 Mb
Chr 16:
92.06 – 92.09 Mb
PubMed search [1] [2]

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.[1][2]

Expression of the myo-inositol transport protein is regulated by osmotic stress.[3]

See also[edit]


  1. ^ Berry GT, Mallee JJ, Kwon HM, Rim JS, Mulla WR, Muenke M, Spinner NB (Jul 1995). "The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21". Genomics 25 (2): 507–13. doi:10.1016/0888-7543(95)80052-N. PMID 7789985. 
  2. ^ "Entrez Gene: SLC5A3 solute carrier family 5 (inositol transporters), member 3". 
  3. ^ Lee SD, Choi SY, Lim SW, Lamitina ST, Ho SN, Go WY, Kwon HM (2011). "TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: Organic osmolyte-dependent and -independent pathways". AJP: Renal Physiology 300 (3): F707–F715. doi:10.1152/ajprenal.00227.2010. PMC 3064130. PMID 21209002.  edit

Further reading[edit]