|BCCT family transporter|
BetP (betaine transporter) from Cornyebacterium glutamicum. PDB 3p03
Betaine / Carnitine / Choline Transporters (BCCT) are a family of prokaryotic transport proteins that are specific for compounds containing a quaternary nitrogen atom. The BCCT proteins contain 12 transmembrane regions and are energized by sodium symport. They contain a conserved region with four tryptophans in their central region. All structures solved to date are trimeric.
- Kempf B, Bremer E, Kappes RM (1996). "Three transport systems for the osmoprotectant glycine betaine operate in Bacillus subtilis: characterization of OpuD". J. Bacteriol. 178 (17): 5071–5079. PMC 178300. PMID 8752321.
- Lee SD, Choi SY, Lim SW, Lamitina ST, Ho SN, Go WY, Kwon HM (2011). "TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: Organic osmolyte-dependent and -independent pathways". AJP: Renal Physiology 300 (3): F707–F715. doi:10.1152/ajprenal.00227.2010. PMC 3064130. PMID 21209002.
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