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Solute carrier family 6 (amino acid transporter), member 14
Symbols SLC6A14 ; BMIQ11
External IDs OMIM300444 MGI1890216 HomoloGene38290 IUPHAR: 937 GeneCards: SLC6A14 Gene
RNA expression pattern
PBB GE SLC6A14 219795 at tn.png
More reference expression data
Species Human Mouse
Entrez 11254 56774
Ensembl ENSG00000087916 ENSMUSG00000031089
UniProt Q9UN76 Q9JMA9
RefSeq (mRNA) NM_007231 NM_020049
RefSeq (protein) NP_009162 NP_064433
Location (UCSC) Chr HG1463_PATCH:
115.55 – 115.58 Mb
Chr X:
21.71 – 21.74 Mb
PubMed search [1] [2]

Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) is a protein that in humans is encoded by the SLC6A14 gene.[1][2]


SLC6A14 is a member of the Na(+)- and Cl(−)-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids in an Na(+)- and Cl(−)-dependent manner.[supplied by OMIM][2]


  1. ^ Sloan JL, Mager S (Sep 1999). "Cloning and functional expression of a human Na(+) and Cl(−)-dependent neutral and cationic amino acid transporter B(0+)". J Biol Chem 274 (34): 23740–5. doi:10.1074/jbc.274.34.23740. PMID 10446133. 
  2. ^ a b "Entrez Gene: SLC6A14 solute carrier family 6 (amino acid transporter), member 14". 

Further reading[edit]

  • Ohman M, Oksanen L, Kaprio J, Koskenvuo M, Mustajoki P, Rissanen A et al. (2000). "Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24". J. Clin. Endocrinol. Metab. 85 (9): 3183–90. doi:10.1210/jc.85.9.3183. PMID 10999806. 
  • Sloan JL, Grubb BR, Mager S (2003). "Expression of the amino acid transporter ATB 0+ in lung: possible role in luminal protein removal". Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1): L39–49. doi:10.1152/ajplung.00164.2002 (inactive 2015-01-01). PMID 12388375. 
  • Suviolahti E, Oksanen LJ, Ohman M, Cantor RM, Ridderstrale M, Tuomi T et al. (2004). "The SLC6A14 gene shows evidence of association with obesity". J. Clin. Invest. 112 (11): 1762–72. doi:10.1172/JCI200317491. PMC 281637. PMID 14660752. 
  • Durand E, Boutin P, Meyre D, Charles MA, Clement K, Dina C et al. (2004). "Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians". Diabetes 53 (9): 2483–6. doi:10.2337/diabetes.53.9.2483. PMID 15331564. 
  • Gupta N, Miyauchi S, Martindale RG, Herdman AV, Podolsky R, Miyake K et al. (2005). "Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans". Biochim. Biophys. Acta 1741 (1–2): 215–23. doi:10.1016/j.bbadis.2005.04.002. PMID 15905073.