SLCO1A2

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Solute carrier organic anion transporter family, member 1A2
Identifiers
Symbols SLCO1A2 ; OATP; OATP-A; OATP1A2; SLC21A3
External IDs OMIM602883 MGI1351896 HomoloGene56603 ChEMBL: 1743123 GeneCards: SLCO1A2 Gene
RNA expression pattern
PBB GE SLCO1A2 207308 at tn.png
PBB GE SLCO1A2 211480 s at tn.png
PBB GE SLCO1A2 211481 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6579 108096
Ensembl ENSG00000084453 ENSMUSG00000063975
UniProt P46721 Q91YY5
RefSeq (mRNA) NM_005075 NM_001267707
RefSeq (protein) NP_066580 NP_001254636
Location (UCSC) Chr 12:
21.42 – 21.57 Mb
Chr 6:
142.23 – 142.32 Mb
PubMed search [1] [2]

Solute carrier organic anion transporter family member 1A2 is a protein that in humans is encoded by the SLCO1A2 gene.[1][2]

This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.[2]

See also[edit]

References[edit]

  1. ^ Kullak-Ublick GA, Beuers U, Meier PJ, Domdey H, Paumgartner G (Apr 1997). "Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization". J Hepatol 25 (6): 985–7. doi:10.1016/S0168-8278(96)80307-2. PMID 9007731. 
  2. ^ a b "Entrez Gene: SLCO1A2 solute carrier organic anion transporter family, member 1A2". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.