SLK (gene)

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STE20-like kinase
Protein SLK PDB 2j51.png
PDB rendering based on 2j51.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols SLK ; LOSK; STK2; bA16H23.1; se20-9
External IDs MGI103241 HomoloGene22515 ChEMBL: 4202 GeneCards: SLK Gene
EC number
RNA expression pattern
PBB GE SLK 206874 s at tn.png
PBB GE SLK 206875 s at tn.png
More reference expression data
Species Human Mouse
Entrez 9748 20874
Ensembl ENSG00000065613 ENSMUSG00000025060
UniProt Q9H2G2 O54988
RefSeq (mRNA) NM_014720 NM_001164639
RefSeq (protein) NP_055535 NP_001158111
Location (UCSC) Chr 10:
105.73 – 105.79 Mb
Chr 19:
47.58 – 47.65 Mb
PubMed search [1] [2]

STE20-like serine/threonine-protein kinase is an enzyme that in humans is encoded by the SLK gene.[1][2]


SLK (gene) has been shown to interact with PDZK1.[3]


  1. ^ Celenza JL, Carlson M (Sep 1986). "A yeast gene that is essential for release from glucose repression encodes a protein kinase". Science 233 (4769): 1175–80. doi:10.1126/science.3526554. PMID 3526554. 
  2. ^ "Entrez Gene: SLK STE20-like kinase (yeast)". 
  3. ^ Gisler, Serge M; Pribanic Sandra, Bacic Desa, Forrer Patrik, Gantenbein Andrea, Sabourin Luc A, Tsuji Akira, Zhao Zhuo-Shen, Manser Edward, Biber Jürg, Murer Heini (Nov 2003). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells". Kidney Int. (United States) 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. ISSN 0085-2538. PMID 14531806. 

Further reading[edit]