SMC4

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Structural maintenance of chromosomes 4
Identifiers
Symbols SMC4 ; CAP-C; CAPC; SMC-4; SMC4L1; hCAP-C
External IDs OMIM605575 MGI1917349 HomoloGene4015 GeneCards: SMC4 Gene
RNA expression pattern
PBB GE SMC4 201664 at tn.png
PBB GE SMC4 201663 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10051 70099
Ensembl ENSG00000113810 ENSMUSG00000034349
UniProt Q9NTJ3 Q8CG47
RefSeq (mRNA) NM_001002799 NM_133786
RefSeq (protein) NP_001002800 NP_598547
Location (UCSC) Chr 3:
160.12 – 160.15 Mb
Chr 3:
69 – 69.03 Mb
PubMed search [1] [2]

Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded by the SMC4 gene.[1][2][3] SMC-4 is a core subunit of condensin I and II, large protein complexes involved in chromosome condensation

References[edit]

  1. ^ Schmiesing JA, Ball AR Jr, Gregson HC, Alderton JM, Zhou S, Yokomori K (Nov 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics". Proc Natl Acad Sci U S A 95 (22): 12906–11. doi:10.1073/pnas.95.22.12906. PMC 23650. PMID 9789013. 
  2. ^ Nishiwaki T, Daigo Y, Kawasoe T, Nagasawa Y, Ishiguro H, Fujita M, Furukawa Y, Nakamura Y (Jun 1999). "Isolation and characterization of a human cDNA homologous to the Xenopus laevis XCAP-C gene belonging to the structural maintenance of chromosomes (SMC) family". J Hum Genet 44 (3): 197–202. doi:10.1007/s100380050142. PMID 10319587. 
  3. ^ "Entrez Gene: SMC4 structural maintenance of chromosomes 4". 

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