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Smith-Magenis syndrome chromosome region, candidate 7-like
Symbols SMCR7L ; HSU79252; MID51; MIEF1; dJ1104E15.3
External IDs MGI2146020 HomoloGene10374 GeneCards: SMCR7L Gene
RNA expression pattern
PBB GE SMCR7L 204593 s at tn.png
PBB GE SMCR7L 204594 s at tn.png
PBB GE SMCR7L 221516 s at tn.png
More reference expression data
Species Human Mouse
Entrez 54471 239555
Ensembl ENSG00000100335 ENSMUSG00000022412
UniProt Q9NQG6 Q8BGV8
RefSeq (mRNA) NM_019008 NM_178719
RefSeq (protein) NP_061881 NP_848834
Location (UCSC) Chr 22:
39.9 – 39.91 Mb
Chr 15:
80.23 – 80.25 Mb
PubMed search [1] [2]

Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.[1][2][3]


The SMCR7L gene codes for a protein that has been called MiD51/MIEF1 and shown to regulate mitochondrial fission by interacting with the proteins Drp1 and FIS1.[4]


  1. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. 
  2. ^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  3. ^ "Entrez Gene: SMCR7L Smith-Magenis syndrome chromosome region, candidate 7-like". 
  4. ^ Dikov, D.; Reichert, A. S. (2011). "How to split up: Lessons from mitochondria". The EMBO Journal 30 (14): 2751–2753. doi:10.1038/emboj.2011.219. PMC 3160261. PMID 21772324.  edit

Further reading[edit]