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Sorting nexin 18
Symbols SNX18 ; SH3PX2; SH3PXD3B; SNAG1
External IDs MGI2137642 HomoloGene14164 GeneCards: SNX18 Gene
Species Human Mouse
Entrez 112574 170625
Ensembl ENSG00000178996 ENSMUSG00000042364
UniProt Q96RF0 Q91ZR2
RefSeq (mRNA) NM_001102575 NM_130796
RefSeq (protein) NP_001096045 NP_570614
Location (UCSC) Chr 5:
53.81 – 53.84 Mb
Chr 13:
113.59 – 113.62 Mb
PubMed search [1] [2]

Sorting nexin-18 is a protein that in humans is encoded by the SNX18 gene.[1][2][3]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. The specific function of this protein has not been determined.[3]


  1. ^ Seet LF, Hong W (Sep 2006). "The Phox (PX) domain proteins and membrane traffic". Biochim Biophys Acta 1761 (8): 878–96. doi:10.1016/j.bbalip.2006.04.011. PMID 16782399. 
  2. ^ Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J (Sep 2007). "A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells". FEBS Lett 581 (23): 4455–62. doi:10.1016/j.febslet.2007.08.025. PMID 17761170. 
  3. ^ a b "Entrez Gene: SNAG1 sorting nexin associated golgi protein 1". 

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