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Salt-inducible kinase 2
Symbols SIK2 ; LOH11CR1I; QIK; SNF1LK2
External IDs OMIM608973 MGI2445031 HomoloGene22875 ChEMBL: 5699 GeneCards: SIK2 Gene
EC number
Species Human Mouse
Entrez 23235 235344
Ensembl ENSG00000170145 ENSMUSG00000037112
UniProt Q9H0K1 Q8CFH6
RefSeq (mRNA) NM_015191 NM_178710
RefSeq (protein) NP_056006 NP_848825
Location (UCSC) Chr 11:
111.47 – 111.6 Mb
Chr 9:
50.89 – 51.01 Mb
PubMed search [1] [2]

Serine/threonine-protein kinase SIK2 is an enzyme that in humans is encoded by the SIK2 gene.[1][2]


SNF1LK2 has been shown to interact with CRTC2.[3]


  1. ^ Katoh M, Katoh M (April 2004). "Identification and characterization of human FOXN5 and rat Foxn5 genes in silico". Int J Oncol 24 (5): 1339–44. doi:10.3892/ijo.24.5.1339. PMID 15067358. 
  2. ^ "Entrez Gene: SNF1LK2 SNF1-like kinase 2". 
  3. ^ Screaton, Robert A; Conkright Michael D, Katoh Yoshiko, Best Jennifer L, Canettieri Gianluca, Jeffries Shawn, Guzman Ernesto, Niessen Sherry, Yates John R, Takemori Hiroshi, Okamoto Mitsuhiro, Montminy Marc (October 2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector". Cell (United States) 119 (1): 61–74. doi:10.1016/j.cell.2004.09.015. ISSN 0092-8674. PMID 15454081. 

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