SNRPB2

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Small nuclear ribonucleoprotein polypeptide B
Protein SNRPB2 PDB 1a9n.png
PDB rendering based on 1a9n.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SNRPB2 ; Msl1
External IDs OMIM603520 MGI104805 HomoloGene37728 GeneCards: SNRPB2 Gene
RNA expression pattern
PBB GE SNRPB2 202505 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6629 20639
Ensembl ENSG00000125870 ENSMUSG00000008333
UniProt P08579 Q9CQI7
RefSeq (mRNA) NM_003092 NM_021335
RefSeq (protein) NP_003083 NP_067310
Location (UCSC) Chr 20:
16.71 – 16.72 Mb
Chr 2:
143.06 – 143.07 Mb
PubMed search [1] [2]

U2 small nuclear ribonucleoprotein B is a protein that in humans is encoded by the SNRPB2 gene.[1][2]

The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.[2]

References[edit]

  1. ^ Habets WJ, Sillekens PT, Hoet MH, Schalken JA, Roebroek AJ, Leunissen JA, van de Ven WJ, van Venrooij WJ (May 1987). "Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen". Proc Natl Acad Sci U S A 84 (8): 2421–5. doi:10.1073/pnas.84.8.2421. PMC 304663. PMID 2951739. 
  2. ^ a b "Entrez Gene: SNRPB2 small nuclear ribonucleoprotein polypeptide B". 

Further reading[edit]