SNTG1

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Syntrophin, gamma 1
Identifiers
Symbols SNTG1 ; G1SYN; SYN4
External IDs OMIM608714 MGI1918346 HomoloGene56834 GeneCards: SNTG1 Gene
RNA expression pattern
PBB GE SNTG1 220405 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 54212 71096
Ensembl ENSG00000147481 ENSMUSG00000025909
UniProt Q9NSN8 Q925E1
RefSeq (mRNA) NM_018967 NM_027671
RefSeq (protein) NP_061840 NP_081947
Location (UCSC) Chr 8:
50.82 – 51.71 Mb
Chr 1:
8.36 – 9.3 Mb
PubMed search [1] [2]

Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.[1][2]

The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.[2]

References[edit]

  1. ^ Piluso G, Mirabella M, Ricci E, Belsito A, Abbondanza C, Servidei S, Puca AA, Tonali P, Puca GA, Nigro V (Jun 2000). "Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells". J Biol Chem 275 (21): 15851–60. doi:10.1074/jbc.M000439200. PMID 10747910. 
  2. ^ a b "Entrez Gene: SNTG1 syntrophin, gamma 1". 

Further reading[edit]