SNX26

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Rho GTPase activating protein 33
Identifiers
Symbols ARHGAP33 ; NOMA-GAP; SNX26; TCGAP
External IDs OMIM614902 MGI2673998 HomoloGene76448 GeneCards: ARHGAP33 Gene
Orthologs
Species Human Mouse
Entrez 115703 233071
Ensembl ENSG00000004777 ENSMUSG00000036882
UniProt O14559 Q80YF9
RefSeq (mRNA) NM_001172630 NM_178252
RefSeq (protein) NP_001166101 NP_839983
Location (UCSC) Chr 19:
36.27 – 36.28 Mb
Chr 7:
30.52 – 30.53 Mb
PubMed search [1] [2]

TC10/CDC42 GTPase-activating protein is an enzyme that in humans is encoded by the SNX26 gene.[1][2][3]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.[3]

References[edit]

  1. ^ Peck J, Douglas G 4th, Wu CH, Burbelo PD (Sep 2002). "Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships". FEBS Lett 528 (1-3): 27–34. doi:10.1016/S0014-5793(02)03331-8. PMID 12297274. 
  2. ^ Worby CA, Dixon JE (Dec 2002). "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol 3 (12): 919–31. doi:10.1038/nrm974. PMID 12461558. 
  3. ^ a b "Entrez Gene: SNX26 sorting nexin 26". 

Further reading[edit]