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Sorting nexin 3
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols SNX3 ; Grd19; MCOPS8; SDP3
External IDs OMIM605930 MGI1860188 HomoloGene36144 GeneCards: SNX3 Gene
RNA expression pattern
PBB GE SNX3 213545 x at tn.png
PBB GE SNX3 210648 x at tn.png
More reference expression data
Species Human Mouse
Entrez 8724 54198
Ensembl ENSG00000112335 ENSMUSG00000019804
UniProt O60493 Q78ZM0
RefSeq (mRNA) NM_001300928 NM_017472
RefSeq (protein) NP_001287857 NP_059500
Location (UCSC) Chr 6:
108.53 – 108.58 Mb
Chr 10:
42.5 – 42.54 Mb
PubMed search [1] [2]

Sorting nexin-3 is a protein that in humans is encoded by the SNX3 gene.[1][2]

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking.[2]


  1. ^ Haft CR, de la Luz Sierra M, Barr VA, Haft DH, Taylor SI (Dec 1998). "Identification of a Family of Sorting Nexin Molecules and Characterization of Their Association with Receptors". Mol Cell Biol 18 (12): 7278–87. PMC 109309. PMID 9819414. 
  2. ^ a b "Entrez Gene: SNX3 sorting nexin 3". 

Further reading[edit]