California State Route 221
|Defined by S&HC § 521|
|Maintained by Caltrans|
|Length:||2.682 mi (4.316 km)|
|South end:||SR 12 / SR 29 near Vallejo|
|North end:||SR 121 in Napa|
Route 221 is the northernmost part of the Napa-Vallejo Highway. It is a divided four-lane expressway that serves as an alternate to the nearby Route 29 freeway into Napa from the south. The southern terminus is with Route 29 (which also carries Route 12), where it continues as the Napa-Vallejo Highway, and the northern terminus is an intersection with Route 121. Route 221 also provides direct access to Napa Valley College and Napa State Hospital.
Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, and do not necessarily reflect current mileage. R reflects a realignment in the route since then. The entire route is in Napa County.
|0.00||Soscol Ferry Road||Continuation beyond SR 12 / SR 29|
|0.00||SR 12 / SR 29 – Sonoma, Calistoga, Vallejo, Oakland|
|Napa||2.68||SR 121 (Imola Avenue, Soscol Avenue) – Lake Berryessa, Sonoma, Downtown Napa|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi