STK19

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Serine/threonine kinase 19
Identifiers
Symbols STK19 ; D6S60; D6S60E; G11; HLA-RP1; RP1
External IDs OMIM604977 MGI1860085 HomoloGene10449 GeneCards: STK19 Gene
EC number 2.7.11.1
RNA expression pattern
PBB GE STK19 36019 at tn.png
PBB GE STK19 204090 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8859 54402
Ensembl ENSG00000204344 ENSMUSG00000061207
UniProt P49842 Q9JHN8
RefSeq (mRNA) NM_004197 NM_019442
RefSeq (protein) NP_004188 NP_062315
Location (UCSC) Chr 6:
31.94 – 31.95 Mb
Chr 17:
34.82 – 34.84 Mb
PubMed search [1] [2]

Serine/threonine-protein kinase 19 is an enzyme that in humans is encoded by the STK19 gene.[1][2][3]

This gene encodes a serine/threonine kinase which localizes predominantly to the nucleus. Its specific function is unknown; it is possible that phosphorylation of this protein is involved in transcriptional regulation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 and expresses two transcript variants.[3]

References[edit]

  1. ^ Sargent CA, Anderson MJ, Hsieh SL, Kendall E, Gomez-Escobar N, Campbell RD (Jul 1994). "Characterisation of the novel gene G11 lying adjacent to the complement C4A gene in the human major histocompatibility complex". Hum Mol Genet 3 (3): 481–8. doi:10.1093/hmg/3.3.481. PMID 8012361. 
  2. ^ Gomez-Escobar N, Chou CF, Lin WW, Hsieh SL, Campbell RD (Dec 1998). "The G11 gene located in the major histocompatibility complex encodes a novel nuclear serine/threonine protein kinase". J Biol Chem 273 (47): 30954–60. doi:10.1074/jbc.273.47.30954. PMID 9812991. 
  3. ^ a b "Entrez Gene: STK19 serine/threonine kinase 19". 

Further reading[edit]