STRAP

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Serine/threonine kinase receptor associated protein
Identifiers
Symbols STRAP ; MAWD; PT-WD; UNRIP
External IDs OMIM605986 MGI1329037 HomoloGene43881 GeneCards: STRAP Gene
Orthologs
Species Human Mouse
Entrez 11171 20901
Ensembl ENSG00000023734 ENSMUSG00000030224
UniProt Q9Y3F4 Q9Z1Z2
RefSeq (mRNA) NM_007178 NM_011499
RefSeq (protein) NP_009109 NP_035629
Location (UCSC) Chr 12:
16.04 – 16.06 Mb
Chr 6:
137.74 – 137.75 Mb
PubMed search [1] [2]

Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAP gene.[1]


Interactions[edit]

STRAP has been shown to interact with Mothers against decapentaplegic homolog 6,[2] TGF beta receptor 2,[2][3] Mothers against decapentaplegic homolog 7,[2] TGF beta receptor 1,[2][3] Mothers against decapentaplegic homolog 3[2] and Mothers against decapentaplegic homolog 2.[2]

References[edit]

  1. ^ "Entrez Gene: STRAP serine/threonine kinase receptor associated protein". 
  2. ^ a b c d e f Datta, P K; Moses H L (May 2000). "STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling". Mol. Cell. Biol. (UNITED STATES) 20 (9): 3157–67. doi:10.1128/MCB.20.9.3157-3167.2000. ISSN 0270-7306. PMC 85610. PMID 10757800. 
  3. ^ a b Datta, P K; Chytil A; Gorska A E; Moses H L (December 1998). "Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling". J. Biol. Chem. (UNITED STATES) 273 (52): 34671–4. doi:10.1074/jbc.273.52.34671. ISSN 0021-9258. PMID 9856985. 

Further reading[edit]