|Systematic (IUPAC) name|
STS-135 (N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide, also called 5F-APICA) is a designer drug offered by online vendors as a cannabimimetic agent. The structure of STS-135 appears to utilise an understanding of structure-activity relationships within the indole class of cannabimimetics, although its design origins are unclear. STS-135 is the terminally-fluorinated analogue of SDB-001, just as AM-2201 is the terminally-fluorinated analogue of JWH-018, and XLR-11 is the terminally-fluorinated analogue of UR-144. No information regarding the in vitro or in vivo activity of STS-135 has been published, and only anecdotal reports are known of its pharmacology in humans or other animals.
A forensic standard of STS-135 is available, and the compound has been posted on the Forendex website of potential drugs of abuse.
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