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Syntaxin 6
Protein STX6 PDB 1lvf.png
PDB rendering based on 1lvf.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbol STX6
External IDs OMIM603944 MGI1926235 HomoloGene115622 GeneCards: STX6 Gene
Species Human Mouse
Entrez 10228 58244
Ensembl ENSG00000135823 ENSMUSG00000026470
UniProt O43752 Q9JKK1
RefSeq (mRNA) NM_001286210 NM_021433
RefSeq (protein) NP_001273139 NP_067408
Location (UCSC) Chr 1:
180.94 – 180.99 Mb
Chr 1:
155.16 – 155.2 Mb
PubMed search [1] [2]

Syntaxin-6 is a protein that in humans is encoded by the STX6 gene.[1][2]


STX6 has been shown to interact with SNAP23,[3] VAMP3[4] and VAMP4.[4]


  1. ^ Martin-Martin B, Nabokina SM, Lazo PA, Mollinedo F (April 1999). "Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1". J Leukoc Biol 65 (3): 397–406. PMID 10080545. 
  2. ^ "Entrez Gene: STX6 syntaxin 6". 
  3. ^ Martín-Martín, B; Nabokina S M; Blasi J; Lazo P A; Mollinedo F (October 2000). "Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis". Blood (UNITED STATES) 96 (7): 2574–83. ISSN 0006-4971. PMID 11001914. 
  4. ^ a b Mallard, Frédéric; Tang Bor Luen, Galli Thierry, Tenza Danièle, Saint-Pol Agnès, Yue Xu, Antony Claude, Hong Wanjin, Goud Bruno, Johannes Ludger (February 2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". J. Cell Biol. (United States) 156 (4): 653–64. doi:10.1083/jcb.200110081. ISSN 0021-9525. PMC 2174079. PMID 11839770. 

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