SURF6

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Surfeit 6
Identifiers
Symbols SURF6 ; RRP14
External IDs OMIM185642 MGI98447 HomoloGene44153 GeneCards: SURF6 Gene
Orthologs
Species Human Mouse
Entrez 6838 20935
Ensembl ENSG00000148296 ENSMUSG00000036160
UniProt O75683 P70279
RefSeq (mRNA) NM_006753 NM_009298
RefSeq (protein) NP_006744 NP_033324
Location (UCSC) Chr 9:
136.2 – 136.2 Mb
Chr 2:
26.89 – 26.9 Mb
PubMed search [1] [2]

Surfeit locus protein 6 is a protein that in humans is encoded by the SURF6 gene.[1][2]

This gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene, being ubiquitously expressed, and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs, which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties, based on characteristics determined in mouse.[2]

References[edit]

  1. ^ Duhig T, Ruhrberg C, Mor O, Fried M (May 1999). "The human Surfeit locus". Genomics 52 (1): 72–8. doi:10.1006/geno.1998.5372. PMID 9740673. 
  2. ^ a b "Entrez Gene: SURF6 surfeit 6". 

Further reading[edit]