SYT7

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Synaptotagmin VII
Protein SYT7 PDB 2d8k.png
PDB rendering based on 2d8k.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SYT7 ; IPCA-7; IPCA7; PCANAP7; SYT-VII; SYTVII
External IDs OMIM604146 MGI1859545 HomoloGene20889 GeneCards: SYT7 Gene
Orthologs
Species Human Mouse
Entrez 9066 54525
Ensembl ENSG00000011347 ENSMUSG00000024743
UniProt O43581 Q9R0N7
RefSeq (mRNA) NM_001252065 NM_018801
RefSeq (protein) NP_001238994 NP_061271
Location (UCSC) Chr 11:
61.28 – 61.35 Mb
Chr 19:
10.39 – 10.45 Mb
PubMed search [1] [2]

Synaptotagmin-7 is a protein that in humans is encoded by the SYT7 gene.[1][2]

Synaptotagmins, such as SYT7, are brain-specific calcium-dependent phospholipid-binding proteins that play a role in synaptic exocytosis and neurotransmitter release. See MIM 600782.[supplied by OMIM][2]

Interactions[edit]

SYT7 has been shown to interact with SYNCRIP.[3]

References[edit]

  1. ^ Cooper PR, Nowak NJ, Higgins MJ, Church DM, Shows TB (August 1998). "Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes". Genomics 49 (3): 419–29. doi:10.1006/geno.1998.5291. PMID 9615227. 
  2. ^ a b "Entrez Gene: SYT7 synaptotagmin VII". 
  3. ^ Mizutani, A; Fukuda M; Ibata K; Shiraishi Y; Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". J. Biol. Chem. (UNITED STATES) 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. ISSN 0021-9258. PMID 10734137. 

Further reading[edit]