Salvia dominica

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Salvia dominica
Salvia dominica.jpg
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Lamiaceae
Genus: Salvia
Species: S. dominica
Binomial name
Salvia dominica
L.
Synonyms

Salvia graveolens Vahl

Salvia dominica (Dominica sage, in Arabic ( Maru = مرو or "Khowwekha" = خويخة ), in (Hebrew: מרווה, marva) is a strong-scented perennial shrub found throughout the eastern Mediterranean, especially Jordan[1] Israel,[2]Lebanon and Syria. The branched inflorescence is one of several salvias thought to have inspired the design of the menorah. It grows to about 1 meter in height and width, and blooms in spring or early summer with pale yellow and white flowers in delicate whorls.[3]

Biological properties[edit]

A group of Italian and Jordanian researchers isolated twenty-four new sesterterpenes, some of them with interesting biological activity due to their interaction with tubulin-tyrosine ligase (TTL), an enzyme involved in the tyrosination cycle of the C-terminal of tubulin, and inhibit TTL activity in cancer cells.[4]

References[edit]

  1. ^ Field Guide of Wild Flower of Jordan and Neighbouring Countries by Dawud Al-Eisawi
  2. ^ Flowers in Israel
  3. ^ Clebsch, Betsy; Barner, Carol D. (2003). The New Book of Salvias. Timber Press. p. 112. ISBN 978-0-88192-560-9. 
  4. ^ Dal Piaz F, Vassallo A, Lepore L, Tosco A, Bader A, De Tommasi N (June 2009). "Sesterterpenes as tubulin tyrosine ligase inhibitors. First insight of structure-activity relationships and discovery of new lead". J. Med. Chem. 52 (12): 3814–28. doi:10.1021/jm801637f. PMID 19459643.