Ali-Khan launched her career in Manchester on a commercial radio station called Sunset 102 in 1989 and then moved to the BBC in 1997 after returning to university for a masters in TV features and documentary production. After moving to Birmingham in 2000 she hosted Drive on the BBC Asian Network and Radio 5 Live. She joined ITV Central in 2005.
Ali-Khan was previously a presenter of the East edition of Central Tonight alongside Steve Clamp, before she left to go maternity leave in mid-2008. She returned on 2 February 2009, co-presenting the West Midlands edition of the programme before it was merged with the East Midlands edition a fortnight later.
Ali-Khan presented the ITV Weekend News on occasion during 2006.
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