After the death of Sampson I in 1725 his sons Charles and Sampson II bought the Town Mill and traded in iron. Sampson II (1699–1779) also bought a forge in Burton upon Trent. After Charles' death in 1741, Sampson II became wealthy and in 1742 bought an Elizabethan house in (then rural) Sparkbrook called "The Farm" for £1,290. He built a Georgian house there, now a grade II* listed building, but continued to live in Edgbaston Street.
In 1765, at the age of 66, he formed a company with the button maker John Taylor (1711–1775) and his own son, Sampson III, creating Birmingham's first bank: Taylor's and Lloyds, located at 7 Dale End. This is the bank which became Lloyds Bank, and then Lloyds TSB.
Another son of Sampson II, Charles Lloyd (1748–1828), was also a partner in the bank as well as a poet and campaigner against slavery. He lived, and died, in Bingley House on Broad Street, later demolished to build the Bingley Hall, itself demolished for the International Convention Centre and Symphony Hall. His son, Charles Lloyd II, unsuccessful poet, was only briefly involved in the bank and moved to Versailles and died in 1839.
- A History of Birmingham, Chris Upton, 1993, ISBN 0-85033-870-0
- The Lloyds of Lloyds Bank - An examination into Family History, Gilbert.