Samuel L. Stanley
|Samuel L. Stanley Jr.|
January 11, 1954 |
Seattle, Washington, U.S.
|Residence||Stony Brook, NY, US|
|Alma mater||University of Chicago
Harvard Medical School
Washington University School of Medicine
|Predecessor||Shirley Strum Kenny|
|Spouse(s)||Dr. Ellen Li|
Samuel Leonard Stanley, Jr. (born January 11, 1954) is an American educator, biomedical researcher and the fifth president of the State University of New York at Stony Brook. He formerly served as the Vice Chancellor for Research at Washington University in St. Louis.[dead link][dead link]
On May 12, 2009 Stanley was named the 5th president of Stony Brook University, a position he formally assumed on July 1, 2009 making him the first physician ever to serve as Stony Brook University’s president. Stanley is one of the founding directors of the Midwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research.[dead link][dead link]
- 1 Education and Early Career
- 2 Appointment as President of Stony Brook University
- 3 Biomedical Research
- 4 Family
- 5 Professional Societies and Organizations
- 6 Patents
- 7 Recent Publications
- 8 References
- 9 External links
Education and Early Career
College of the University of Chicago
Samuel L. Stanley, Jr. graduated from The College of the University of Chicago with honors in Biological Sciences in 1976 and was inducted into Phi Beta Kappa in 1976. As an undergraduate, Stanley also served as a teaching assistant in Biology at the University of Chicago.
Harvard Medical School
As an Albert Schweitzer fellow of Harvard Medical School, Stanley received his M.D. specializing in Internal Medicine in 1980. He served as a medical intern at Massachusetts General Hospital between 1980 and 1981 and stayed to complete his residency in Internal Medicine at Massachusetts General Hospital. Here, he was appointed as an Associate member of the American College of Physicians. During his time at Mass General, Stanley met colleague and future wife, Dr. Ellen Li who was concurrently completing her residency in internal medicine.
Washington University School of Medicine
Between 1983 and 1984, Stanley completed his fellowship (medicine) in infectious diseases at Washington University School of Medicine in St. Louis. While there, he was also awarded a Pfizer fellowship in microbiology and immunology. He quickly rose through the ranks to be appointed as a professor in the departments of medicine, molecular biology and infectious diseases. In 1989 he became a member of the Infectious Diseases Society of America and the American Federation for Clinical Research. In 2006, he was named the vice-chancellor for research at Washington University. “In this role, he oversaw a research portfolio of $548 million, including $391 million in NIH funding. His responsibilities encompassed a broad array of activities associated with the management of these extramural research funds, including, but not limited to, the full range of matters related to undergraduate, graduate, and faculty research, and technology transfer.”
Appointment as President of Stony Brook University
In May 2009, Dr. Samuel L. Stanley, Jr. was named the fifth president of Stony Brook University. Using his established expertise in academic administration and clinical research, Dr. Stanley has overseen several innovative initiatives. Under his supervision, “Project 50 Forward”, one of the pivotal enterprises that Stony Brook University has embarked upon in its 53-year history, was launched. “With input from a 16-member Steering Committee, Project 50 Forward focuses on every facet of University operations – streamlining procedures, reining in costs, creating new revenue streams, and taking advantage of every opportunity to strengthen [the] faculty and support students by providing them with the resources they need to excel”. In his inaugural address Stanley stated, “Stony Brook and SUNY are ready, willing, and able to play a central role in creating the Long Island and New York of the future”. With the projects already underway (along with the assistance of the management firm Bain & Co.) Stanley strives to focus on “operational excellence,” “academic greatness” and “building for the future” at Stony Brook University.
On January 26, 2012, Dr. Stanley and his wife Dr. Li announced the establishment of the “Ellen Li and Samuel L. Stanley Jr. Endowed Scholarship” in the Stony Brook University School of Medicine. This merit-based scholarship will provide critical financial assistance to young people who have received their undergraduate degree through Stony Brook’s Educational Opportunity Program/Advancement on Individual Merit (EOP/AIM) and who aspire to careers as physician-scientists. It was also under Dr. Stanley’s presidency that Stony Brook University saw the 6th largest donation to a public university, and the largest gift in SUNY’s history, from philanthropists James Simons and his wife, Marilyn Simons. “Part of the Simons Gift was an Academic Excellence Challenge Grant to match donations intended for undergraduate scholarships and graduate fellowships, to retain and recruit outstanding faculty, and to enhance academic programs, institutes, and centers of excellence." Thus now, every donation to Stony Brook University is doubled, with the Simons Foundation matching every gift. Stanley currently serves on the SUNY Strategic Planning Steering Committee which will guide the development of the State University of New York over the next decade.
Stanley is also on the Board of Trustees at Cold Spring Harbor Laboratory and on the Board of Brookhaven Science Associates LLC.(which is responsible for the management of Brookhaven National Laboratory). According to the SUNY Research Foundation, by playing an active role in the maintenance of large research projects, "Dr. Stanley joins the leaders of a select group of prestigious academic institutions including Cornell, Princeton, Stanford, the University of California-Berkeley, and the University of Chicago in co-managing and collaborating with a national laboratory."
Stanley is a distinguished biomedical researcher and a prominent name among experts on infectious diseases. His research interest in immunity from infections has led him to publish several scholarly articles about the characterization of key proteins and pathways involved in amebic, bacterial and viral infections, blood-borne pathogen risks in hemophilia therapy, and the identification of new strain- specific clones. Better defense against infection is a key focus of his research. “Recently he has begun to focus as well on specific genetic factors that might make serious side effects more common in some persons receiving vaccines”.
In 2008, he worked to create the Midwest Regional Center for Excellence in Biodefense and Emerging Infectious Diseases Research, with a $37 million grant from the National Institutes of Health. The center was established with goals of improving biodefense, in reaction to the post September 11 bioterrorism threats and anthrax attacks. He has also served on the National Science Advisory Board for Biosecurity, the NIH Blue Ribbon Panel on the New England Infectious Diseases Research Laboratory, the NIH National Advisory Allergy & Infectious Diseases Council and committees led by the United States Department of Commerce.
Dr. Stanley is also the recipient of numerous awards, including the Burrough’s Welcome Scholar Award in Molecular Parasitology and the Distinguished Service Teaching Award from Washington University. Stanley is currently the owner of 3 patents. He also serves as an ambassador for the Paul G. Rogers Society for Global Health Research and has received an honorary doctorate degree in Science from Konkuk University in South Korea.
Stanley is married to Ellen Li, MD, PhD a practicing gastroenterologist and active researcher. Together, Stanley and Li have four children- James, Susan, Katherine, and Samuel III.[dead link][dead link]
Professional Societies and Organizations
- Associate Member, American College of Physicians, 1981
- Member, Infectious Disease Society of America, 1989
- Member, American Society of Tropical Medicine and Hygiene, 1988
- Member, American Federation for Clinical Research, 1989
- Member, American Society for Microbiology, 1992
- Fellow, Infectious Disease Society of America, 1995
- Member, American Society for Clinical Investigation, 1995
- Secretary-Treasurer, Board of Directors, Infectious Diseases Society of St. Louis, 2004-2007
US Patent 5,130,147: Entamoeba histolytica Immunogenic protein and cDNA clone. Significance: patent of the SREHP cDNA clone; recombinant SREHP is a major vaccine candidate for amebiasis, and a reagent utilized in prototype diagnostic tests. Inventor: Samuel L. Stanley Jr., and Ellen Li. Assignee: Washington University, St. Louis.
US Patent 5,275,935: Amebic glycoconjugate and monoclonal antibody. Significance: patent of the amebic glycoconjugate, a major surface antigen of amebae and a monoclonal antibody, CC 8.6 which recognizes this antigen. Possible uses in diagnostic kits. Inventor: Samuel L. Stanley, Jr., and Ellen Li. Assignee: Washington University, St. Louis.
US Patent 5,807,000: Method of screening anti-amebic compounds. Significance: Describes the use of mutant E. coli strains complemented with amebic antigens to screen compounds for anti-amebic activity. Inventor: Samuel L. Stanley, Jr. Assignee: Washington University, St. Louis.
- Zhang, Z; Jin, L; Champion, G; Seydel, KB; Stanley Jr, SL. Shigella infection in SCID-HU-INT mice: role for neutrophils in containing bacterial dissemination in human intestine. Infection and Immunity, 2001; 69:3240-3247.
- Stenson, W; Zhang, Z; Riehl, T; Stanley Jr, SL. Amebic infection induces cyclooxygenase-2 (COX-2) production in human intestine. Infection and Immunity, 2001; 69:3382-3388.
- Espinosa, A; Yan, L; Zhang, Z; Foster. L; Clark, D; Li, E; Stanley Jr, SL. The bifunctional Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) protein is necessary for amebic growth and survival and requires an intact C-terminal domain for both alcohol dehydrogenase and acetaldehyde dehydrogenase activity. Journal of Biological Chemistry, 2001, Jun 8; 276(23): 20136-20143.
- Babcock, HM; Ritchie,DJ; Christiansen, E; Starlin, R; Little, R; Stanley Jr, SL. Successful treatment of vancomycin-resistant Enterococcus endocarditis with oral linezolid. Clinical Infectious Diseases, 2001, May 1; 32(9):1373-1375.
- Yan, L; Stanley Jr, SL. Blockade of caspases inhibits amebic liver abscess formation in a mouse model of disease. Infection and Immunity, 2001; 69:7911-7914.
- Zhang, Z; Duchene, M; Stanley Jr, SL. A monoclonal antibody to the amebic lipophosphoglycan/proteophosphoglycan antigens can prevent disease in human intestinal xenografts infected with Entamoeba histolytica. Infection and Immunity, 2002; 70:5873-5876.
- Zhang, Z; Mahajan, S; Zhang, X-C; Stanley Jr, SL. Tumor necrosis factor-α is a key mediator of the gut inflammation seen in amebic colitis in human intestine in the SCID mouse-human intestinal xenograft model of disease. Infection & Immunity, 2003; 71:5355-5359.
- Zhang, X-C; Zhang, Z; Alexander D; Bracha, R; Mirelman, D; Stanley Jr, SL. Expression of amoebapores is required for full expression of Entamoeba histolytica virulence in amebic liver abscess, but is not necessary for the induction of inflammation or tissue damage in amebic colitis. Infection and Immunity, 2004; 72:678-683.
- Zhang, Z; Stanley Jr, SL. Stereotypic and specific elements of the human colonic response to Entamoeba histolytica and Shigella flexneri infection. Cellular Microbiology, 2004, Jun; 6(6):535-564.
- Espinosa, A; Clark, DC; Stanley Jr, SL. Entamoeba histolytica Alcohol Dehydrogenase 2 (EhADH2) as a target for antiamoebic agents. Journal of Antimicrobial Chemotherapy, 2004, Jul; 54(1):56-59.
- Chen, M; Li, E; Stanley Jr, SL. Structural analysis of the acetaldehyde dehydrogenase activity of Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2), a member of the ADHE enzyme family. Molecular & Biochemical Parasitology, 2004; 137:201-205.
- Davis, PH; Zhang, Z; Chen, M; Zhang, XC; Chakraborty, S; Stanley Jr, SL. Identification and characterization of a family of Bsp-A like surface proteins of Entamoeba histolytica with novel leucine rich repeats. Molecular & Biochemical Parasitology, 2006; 145:111-116.
- Pelosoff, L; Davis,PH; Zhang, Z; Zhang, XC; Stanley Jr, SL. Coordinate but disproportionate activation of apoptotic, regenerative, and inflammatory pathways characterizes the liver response to acute amebic infection. Cellular Microbiology, 2006, Mar; 8(3):508-522.
- Stanley Jr, SL. The need for continuing vigilance: addressing the threat for transmission of blood-borne infectious disease. Seminars in Hematology, 2006, Apr; 43(3) Supplement: S17-S22.
- Davis, P; Zhang, X; Guo, J; Townsend, RR; Stanley Jr, SL. Comparative proteomic analysis of two Entamoeba histolytica stains with different virulence phenotypes identifies peroxiredoxin as an important component of amebic virulence. Molecular Microbiology (journal), 2006; 61:1523-1532.
- Ludlam, CA; Powderly, WG; Bozzett, S; Diamond, M; Koerper, MA; Kulkarni, R; Ritchie, B; Siegel, J; Simmonds, P; Stanley Jr, SL; Tapper, ML; von Depka, M. Clinical perspectives of emerging pathogens in bleeding disorders. The Lancet, 2006, Jan 21; 367(9506):252-261.
- Davis, PA; Schulz, J; Stanley Jr, SL. Transcriptomic comparison of two Entamoeba histolytica stains with defined virulence phenotypes identifies new virulence factor candidates and key differences in the expression patterns of cysteine proteases, lectin light chains, and calmodulin. Molecular & Biochemical Parasitology, 2007, Jan; 151(1):118-128.
- http://www.stonybrook.edu/pres/cv.html=all About the President: Curriculum Vitae.
- http://www.stonybrook.edu/pres/bio.html= all Stony Brook University: Office of the President: Biography
- http://investing.businessweek.com/research/stocks/private/person.asp?personId=129279542&privcapId=6184496&previousCapId=6184496&previousTitle=State%20University%20of%20New%20York%20at%20Stony%20Brook=all Company Overview of State University of New York at Stony Brook- People.
- http://www.americaeast.com/ViewArticle.dbml?DB_OEM_ID=14000&ATCLID=3737095=all Samuel Stanley Selected New President at Stony Brook University
- http://news.wustl.edu/news/Pages/6557.aspx=all Vice-Chancellor of Research at Washington University
- http://hms.harvard.edu/alumni-search?LastName=stanley&FirstName=samuel&GradYear=1980&id=DC0eXHkBaUdudBxhNUR6KDsNMB8jEAJjVSYAcyh-GwF1ZQAb= all HMS- Alumni
- http://www.stonybrookphysicians.com/doctor/LI_MD_ELLEN_2884.asp= all Stony Brook Physicians- Ellen LI, M.D., PhD
- http://www.healthgrades.com/physician/dr-samuel-stanley-xmtsj/education=all Dr. Samuel Stanley- Education
- http://www.stonybrook.edu/pres/lady.html=all About the President: First Lady
- http://www.stonybrook.edu/sb/50forward/about_50.html=all About Project 50 Forward
- http://www.stonybrook.edu/sb/inauguration/address.html=all President Stanley's Inaugural Address
- http://www.stonybrookphysicians.com/html_community/news_view.asp?item=392=all stony brook university president Samuel Stanley and his wife Ellen Li make six figure gift
- http://www.nytimes.com/2011/12/14/nyregion/stony-brook-university-given-150-million.html=all Stony Brook University to Get $150 Million Gift
- https://portal.rfsuny.org/portal/page/portal/The%20Research%20Foundation%20of%20SUNY/home/Who_we_are/Board_of_Directors/stanley_bio= all Research Foundation Board Member: Who We Are
- http://www.researchgate.net/researcher/12788669_Samuel_Stanley=all ResearchGate Profile: Samuel L. Stanley
- http://mrce.wustl.edu/index.php?page=about=all About the MRCE
- Overview of State University of New York at Stony Brook- People
- Stony Brook University: Office of the President
- Curriculum Vitae
Shirley Strum Kenny
|President of Stony Brook University