Samuel Tuke (31 July 1784–14 October 1857) was a Quaker philanthropist and mental-health reformer. He was born in York, England.
He greatly advanced the cause of the amelioration of the condition of the insane, and devoted himself largely to the York Retreat. The methods of treatment pursued there were made more widely known by his Description of the Retreat near York. In this work Samuel Tuke referred to the Retreat's methods as moral treatment, borrowed from the French "traitement moral" being used to describe the work of Jean-Baptiste Pussin and Philippe Pinel in France (and in the original French referring more to morale in the sense of the emotions and self-esteem, rather than rights and wrongs). Samuel Tuke also published Practical Hints on the Construction and Economy of Pauper Lunatic Asylums (1815).