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San Polo Matese is a comune (municipality) in the Province of Campobasso in the Italian region Molise, located about 20 kilometres (12 mi) southwest of Campobasso. As of 31 December 2004, it had a population of 465 and an area of 17.7 square kilometres (6.8 sq mi).
San Polo Matese borders the following municipalities: Bojano, Campochiaro, Colle d'Anchise, San Gregorio Matese.
- ^ All demographics and other statistics: Italian statistical institute Istat.