Santo André (Portuguese pronunciation: [sɐ̃twɐ̃ˈdɾɛ], Saint Andrew) is a Brazilian municipality located in the Metropolitan Region of São Paulo, including a group of municipalities known as Greater ABC Region. Its population in 2010 was 676,407. It occupies an area of 175.7 square kilometers, resulting in a population density of 3,848.01 inhabitants per km².
The settlement, which became a town in 1553, with the name of Santo André da Borda do Campo, experienced rapid growth beginning in the 1930s. It was originally named São Bernardo because the municipality district headquarters were in São Bernardo do Campo, now a city nearby. In 1938, the name was changed to Santo André, as the district government was transferred to Santo André. Industries include chemical engineering, textiles, oil, metal products, metallurgy and printed matter. It is an industrial city, but more than 60% of Santo André's total area are protected by environmental water laws.