|Classification and external resources|
Rust-colored spots typical of Schamberg disease on the lower left leg and left foot of a 26-year-old Caucasian male.
Schamberg Disease, (also known as "Progressive pigmentary dermatosis of Schamberg," "Purpura pigmentosa progressiva," and "Schamberg's purpura") is a chronic discoloration of the skin found in people of all ages, usually affecting the legs. It slowly spreads throughout the body, and is most common in males.:829 It is named after Jay Frank Schamberg, who described it in 1901.
Schamberg's disease, or progressive pigmented purpuric dermatitis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward.
Schamberg's disease is caused by leaky blood vessels near the surface of the skin, capillaries, which allow red blood cells to slip through into the skin. The red blood cells in the skin then fall apart and release their iron which causes a rust color, this accounts for the orange tint of the rash.
The lesions are most frequent on the lower limbs, but may occur anywhere on the body, including the hands, arms, torso and even the neck. They may vary in number and erupt in mass numbers. They consist of irregular patches of orange or brown pigmentation due to hemosiderin (iron), with characteristic "cayenne pepper" spots appearing within and at the edge of old lesions. There are usually no symptoms, although there may be some slight itching. The eruption may persist for many years. The pattern of the eruption changes, with slow extension and often some clearing of the original lesions.
See also 
- Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- Geller M (September 2000). "Benefit of colchicine in the treatment of Schamberg's disease". Ann. Allergy Asthma Immunol. 85 (3): 246. doi:10.1016/S1081-1206(10)62476-3. PMID 11030283.
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