Schiller's iodine solution is applied to the cervix under direct vision. Normal cervical mucosa contains glycogen and stains brown, whereas abnormal areas, such as early cervical cancer, do not take up the stain. The abnormal areas can then be biopsied and examined histologically. Composition of Schiller's iodine is same as Lugol's iodine, latter been more concentrated. When Schiller's iodine is not available, Lugol's iodine can be used as an alternative.
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