Schlosser's base

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Schlosser's base describes various superbasic mixtures of an alkyllithium compound and a potassium alkoxide. Commonly, the mixture is formed by combining n-butyllithium and potassium tert-butoxide in a one-to-one ratio. The reagent is named after Manfred Schlosser, though he uses the term LICKOR superbase (LIC denoting the alkyllithium, and KOR denoting the potassium alkoxide).

Further reading[edit]

  • Schlosser, Manfred (1988). "Superbases for organic synthesis". Pure and Applied Chemistry 60 (11): 1627–1634. doi:10.1351/pac198860111627. 
  • Schlosser, Manfred (2005-01-07). "The 2×3 Toolbox of Organometallic Methods for Regiochemically Exhaustive Functionalization". Angewandte Chemie International Edition 44 (3): 376–393. doi:10.1002/anie.200300645. PMID 15558637.