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|Industry||science and health technology
software publisher NAICS 511210
|Founder(s)||Richard A. Friesner,
|Key people||Ramy Farid (President),Murco Ringnalda (CFO)|
|Revenue||about $20 million (2012)|
|Employees||240 total as of Sep 2013|
Schrödinger, LLC is an American software company based in Portland, Oregon. It was founded in 1990. It primarily develops scientific simulation software for biotechnology and pharmaceutical applications.
Ringnalda, who is a native of Portland, OR found the company in 1990 in Texas while he was a student. In 1996, it relocated to Portland, OR
Schrodinger's major offices are located in Portland and New York. Bill Gates had invested $10 million in 2010 through his investment company Cascade under conditions that it is to be spent only for research and development. Gates invested another $20 million in Schrodinger in December 2012
Schrodinger develops software for use in biotechnology and pharmaceutical applications, such as molecular modeling software package
|This section is incomplete. (August 2013)|
Molecular modeling, locating protein binding sites are some examples of functions provided by its software. Python APIs exist for most of the software tools developed by Schrödinger, making it possible to build custom workflows. Some of its software are: Canvas Glide, Induced Fit Phase SiteMap, WaterMap
- "biz journal". Dec 2012. Retrieved 28 August 2013.
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- "Business Week". http://investing.businessweek.com/research/stocks/private/snapshot.asp?privcapid=517729.
- Duan, J.; Dixon, S.L.; Lowrie, J.F.; Sherman, W. (2010). "Analysis and Comparison of 2D Fingerprints: Insights into Database Screening Performance Using Eight Fingerprint Methods". J. Molec. Graph. Model. 29 (2): 157–170. doi:10.1016/j.jmgm.2010.05.008. PMID 20579912.
- Friesner, R. A.; Murphy, R. B.; Repasky, M. P.; Frye, L. L.; Greenwood, J. R.; Halgren,T. A.; Sanschagrin, P. C.; Mainz, D. T. (2006). "Extra Precision Glide: Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein-Ligand Complexes". Journal of Medicinal Chemistry 49 (21): 6177–6196. doi:10.1021/jm051256o. PMID 17034125.
- Sherman, W.; Day, T.; Jacobson, M. P.; Friesner, R. A.; Farid, R. (2006). "Novel Procedure for Modeling Ligand/Receptor Induced Fit Effects". Journal of Medicinal Chemistry 49 (2): 534–553. doi:10.1021/jm050540c. PMID 16420040.
- Dixon, S. L.; Smondyrev, A. M.; Knoll, E. H.; Rao, S. N.; Shaw, D. E.; Friesner, R. A. (2006). "PHASE: A New Engine for Pharmacophore Perception, 3D QSAR Model Development, and 3D Database Screening. 1. Methodology and Preliminary Results". J. Comput. Aided Mol. Des. 20 (10-11): 647–671. doi:10.1007/s10822-006-9087-6. PMID 17124629.
- Halgren, T. (2009). "Identifying and Characterizing Binding Sites and Assessing Druggability". J. Chem. Inf. Model. 49 (2): 377–389. doi:10.1021/ci800324m. PMID 19434839.
- Robert Abel, Tom Young, Ramy Farid, Bruce J. Berne, Richard A. Friesner (2008). "Role of the Active-Site Solvent in the Thermodynamics of Factor Xa Ligand Binding". J. Am. Chem. Sco. 130 (9): 2817–2831. doi:10.1021/ja0771033. PMID 18266362.