Sclerema neonatorum

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Sclerema neonatorum
Classification and external resources
ICD-10	P83.0
ICD-9	778.1
DiseasesDB	31401
eMedicine	article/1112191
MeSH	D012593

Sclerema neonatorum is a rare and severe skin condition that is characterized by diffuse hardening of the subcutaneous tissue with minimal inflammation.^[1]^:490^[2] It usually affects premature, ill newborns. Prognosis is poor.

Minimal inflammation helps distinguish sclerema neonaturum from subcutaneous fat necrosis of the newborn.

References [edit]

^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1515, 1524, 1525. ISBN 1-4160-2999-0.

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Disorders of subcutaneous fat (M79.3, 729.3)

Panniculitis

Lobular	without vasculitis: Cytophagic histiocytic panniculitis Factitial panniculitis Gouty panniculitis Pancreatic panniculitis Traumatic panniculitis Cold panniculitis needle-shaped clefts Subcutaneous fat necrosis of the newborn Sclerema neonatorum Post-steroid panniculitis Lipodermatosclerosis Weber–Christian disease Lupus erythematosus panniculitis Sclerosing lipogranuloma with vasculitis: Nodular vasculitis/Erythema induratum

Septal	without vasculitis: Alpha-1 antitrypsin deficiency panniculitis Erythema nodosum Acute erythema nodosum Chronic erythema nodosum with vasculitis: Superficial thrombophlebitis

Lipodystrophy

Acquired	generalized: Acquired generalized lipodystrophy partial: Acquired partial lipodystrophy Centrifugal abdominal lipodystrophy HIV-associated lipodystrophy Lipoatrophia annularis localized: Localized lipodystrophy

Congenital	Congenital generalized lipodystrophy Familial partial lipodystrophy Poland's syndrome

M: INT, SF, LCT

anat/phys/devp

noco (i/b/d/q/u/r/p/m/k/v/f)/cong/tumr (n/e/d), sysi/epon

proc, drug (D2/3/4/5/8/11)

Certain conditions originating in the perinatal period / fetal disease (P, 760–779)

Maternal factors and
complications of pregnancy,
labour and delivery

placenta: Placenta praevia · Placental insufficiency · Twin-to-twin transfusion syndrome

chorion/amnion: Chorioamnionitis

umbilical cord: Umbilical cord prolapse · Nuchal cord · Single umbilical artery

Length of gestation
and fetal growth

Small for gestational age/Large for gestational age · Preterm birth/Postmature birth · Intrauterine growth restriction

Birth trauma

scalp (Cephalhematoma, Chignon, Caput succedaneum, Subgaleal hemorrhage) · Brachial plexus lesion (Erb's palsy, Klumpke paralysis)

By system

Respiratory	Intrauterine hypoxia · Infant respiratory distress syndrome · Transient tachypnea of the newborn · Meconium aspiration syndrome · pleural disease (Pneumothorax, Pneumomediastinum) · Wilson-Mikity syndrome · Bronchopulmonary dysplasia

Cardiovascular	Pneumopericardium · Persistent fetal circulation

Haemorrhagic and hematologic disease	Vitamin K deficiency (Haemorrhagic disease of the newborn) HDN (ABO • Anti-Kell • Rh c • Rh D • Rh E) · Hydrops fetalis · Hyperbilirubinemia (Kernicterus, Neonatal jaundice) Velamentous cord insertion Intraventricular hemorrhage (Germinal matrix hemorrhage) Anemia of prematurity

Digestive	Ileus · Necrotizing enterocolitis · Meconium peritonitis

Integument and temperature regulation	Erythema toxicum · Sclerema neonatorum

Nervous system	Periventricular leukomalacia

Musculoskeletal	Gray baby syndrome · muscle tone (Congenital hypertonia, Congenital hypotonia)