Scott Depot is an unincorporated community in Putnam County, West Virginia, United States. It is located along Crooked Creek at and downstream from the creek's intersection with Teays Valley Road. The zipcode is 25560. It is part of the census-designated place of Teays Valley which is a part of the Huntington-Ashland Metropolitan Statistical Area (MSA). As of the 2010 census, the MSA had a population of 287,702. New definitions from February 28, 2013 placed the population at 363,000.